The Atunse Platforms
Signals, Not Cells.
Instruction, Not Replacement.
Atunse works with four clinical platforms and a regenerative aesthetics collection — each built on the body's own repair language, carried into practice under disciplined clinical governance.
Clinical Platforms
Acellular Signalling Biologic
AVEXO™
The flagship signalling preparation — a cell-free blend of natural repair signals from donated perinatal tissue, screened to a high standard. Delivers a coordinated set of the body's own repair instructions: calming inflammation, supporting new blood-vessel growth, and guiding tissue to remodel and recover.
Areas of Investigation
- Joints & arthritis
- Tendon, ligament & soft-tissue injury
- Chronic and slow-healing wounds
- Cardiovascular tissue repair
CNS-Directed Signalling
KH-1814™
The same signalling approach as Avexo, prepared specifically for the brain and nervous system. Administered through the nose or intravenously to reach delicate neural tissue — aiming to calm inflammation within nerve tissue and support protection and repair of neurons.
Areas of Investigation
- Neurological & neuro-inflammatory conditions
- Neuro-protective and neuro-repair research
- Specialist settings only
Cellular + Signalling
AIOVA™
Pairs living cells drawn from amniotic fluid with a signalling preparation — combining responsive cells with a sustained, supportive signal. Living cells respond to surrounding tissue and add their own signals, while the preparation provides lasting support within an injured area.
Areas of Investigation
- Musculoskeletal — joints, cartilage, discs
- Selected metabolic conditions
Signalling + Immune Cells
NKIRA™
A two-part immune therapy using natural killer (NK) cells grown from donated cord blood, together with the messenger signals those same cells produce. Messenger signals are given first to prepare the area; NK cells follow into a readied environment where they better recognise and remove abnormal cells.
Areas of Investigation
- Cancer immunotherapy — selected solid tumours
- Specialist oncology units only
- Always alongside standard-of-care
Atunse's clinical platforms are designed to apply this science. They are investigational, and their clinical effects are being studied.
References
1. López-Otín C, et al. Hallmarks of aging: an expanding universe. Cell. 2023;186:243–278.
2. Conboy IM, et al. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature. 2005;433:760–764.
3. Villeda SA, et al. Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat Med. 2014;20:659–663.
4. Yoshida M, et al. Extracellular vesicle-contained eNAMPT delays aging and extends lifespan in mice. Cell Metab. 2019;30:329–342.
5. Kara RJ, et al. Fetal cells traffic to injured maternal myocardium and undergo cardiac differentiation. Circ Res. 2012;110:82–93.
The Atunse Framework
Ageing is a loss of
instructions — not capacity.
The framework holds that ageing and chronic disease are, at their root, a loss of the body's regenerative instructions. Perinatal tissue concentrates the developmental signalling language that builds and heals. Re-supplying that language reawakens the body's own repair program across many conditions that share chronic inflammation and lost signalling as their common root.
Heterochronic parabiosis
Aged tissue regenerates when exposed to young signals — carried by extracellular vesicles, not transferred cells.
Pregnancy proves it
Fetal developmental signals cross into maternal circulation and improve maternal tissue.
Perinatal concentration
Amniotic fluid, cord blood, Wharton's jelly and placenta concentrate this developmental signalling language.
A common root
Cardiometabolic, musculoskeletal, chronic-pain and neurological conditions share inflammation and lost regenerative signalling.
Regenerative Aesthetics Collection
HydroKarma.
The Biology of Renewal.
A collection of premium regenerative aesthetic preparations from HydroKarma, Inc., part of Atunse Global, manufactured by KweHealth — at the heart of which are perinatal-tissue-derived signalling preparations, produced and characterised to a standard drawn from regulatory-grade biologics manufacturing.
Deliberately limited in distribution — offered through Atunse Healthcare and a selected circle of distinguished aesthetic practices. We do not seek volume. We seek the right hands.
A regenerative skin cream worn between professional visits, every morning and evening. Composed around perinatal-derived signalling technology and a considered architecture of botanicals, humectants, and skin-identical lipids.
Supports
- The skin's renewal environment
- Hydration & moisture balance
- A healthy-looking barrier
- Smoother, more resilient skin
- A radiant, even complexion
Composed for daily use. Dermatologically tested. HRIPT tested. For aesthetic use only.
A concentrated regenerative serum created for the hands of the aesthetic professional. Formulated with a high concentration of perinatal-derived signalling factors in a light, rapidly absorbed base — for practitioner-directed protocols including micro-channelling and cosmetic skin-rejuvenation.
Supports
- Concentrated regenerative signalling
- Integration into procedures
- Post-procedure appearance
- A smoother, brighter complexion
- Lightweight and swiftly absorbed
For professional aesthetic use only. Dermatologically tested. HRIPT tested.
Beauty begins at the root. A regenerative preparation for the scalp — the true foundation of beautiful hair. Extends the collection's signalling technology to the scalp, built for the professional's hand within hair-wellness and scalp-rejuvenation programmes.
Supports
- A healthy scalp environment
- Fuller, healthier-looking hair
- Complements professional restoration protocols
For professional aesthetic use only. Dermatologically tested. HRIPT tested.
The HydroKarma System
One continuous arc of care. A treatment is a moment. A ritual is a result.
In the Clinic
Professional tier
Serum 44-C
The instrument
Privée
Daily continuity
REVIAX-C
Hair & scalp
HydroKarma products are cosmetic and aesthetic preparations designated for aesthetic use only. They are not intended to diagnose, treat, cure, or prevent any condition. Claims concern the look and feel of skin and hair only.